You need to see what fits your hand best.....
You need to hold it and feel the balance as you hold it...........
Then consider what use you want it for .. hunting, carrying, home/personal ...
I have had quite a few.... the desert eagle 44... ahhhhhh HUGE and heavy and awsome... but not a carry gun or a quick draw at all...
Glocks are nice adn light and durable.. but I have a big hand and it just dident sit right for me and felt unbalanced when pulling the trigger. Had the Glock 22
H&K ... had the older USP 9mm ... sweet... second favorite.. I could shoot the shit out of anything in my sights. And the 15 rd. clips were nice too

Felt great, light, fast draw and midsize so it was east to conceal but to conceal it all day would not make it my top choice IF your going to carry it.
Sigs = my favorite

I have the 229 with laser grips .... Bottom line is it fits me best. high cap. .40/.357sig clips and feels perfect. It is not light but thats what helps its feel for me. The fit and finnish are awsome and it draws fast and straight.
Personal feel and fitting your needs are the things you need to decide.. but most important is you need to go and hold them bro ...
good luck and POST A PIC !!!!!!!!!!!!!!!!!